Compact Granulation Systems for the pharmaceutical industry

Compact Granulation System BFS and GMA

Low space requirements, flexible use and smooth production processes are decisive criteria when the pharmaceutical industry invests in granulation systems. L.B. Bohle sets standards in this area with its compact granulation systems.

More about the highlights

Granulation with the compact granulation system from L.B. Bohle

The Bohle Compact Granulation System (BFS & GMA) optimally integrates the individual components high-shear granulator GMA, wet screen BTS, fluidised bed granulator and  dryer BFS, Bohle Uni Cone BUC®, cyclone separator and dry screen BTS into a single unit. The process, cleaning, control, explosion protection, zone concept and qualification are closely harmonised.

The compact granulation module allows for a particularly space-saving installation thanks to the components being arranged directly next to each other. In addition, a direct product transfer from the outlet valve of the GMA to the intake valve of the BFS is possible via a stainless steel pipe.

What our customers say

konapharma AG from Switzerland

Compact Granulation System: Optimisation of classic Wet Granulation

Thanks to the numerous technological advances and its coherent safety concept, the compact granulation system sets new industrial standards. The granulation system is the effective solution when it comes to optimising classic wet granulation in an economical and ergonomic way.

Compact Granulation System -
The advantages

  • High-shear granulator and fluid bed granulation right next to each other
  • Bohle Uni Cone BUC® enables complete fluidisation of the particles; uniform filming due to tangential particle movement.
  • Low space requirement and minimum overall height
  • Multi-purpose use for a wide range of processes
  • One control panel to control both machines
  • WIP cleaning guarantees a fast cleaning time
  • Highest product quality

Technical data

Fluidised bed system BFS 30 BFS 60 BFS 120 BFS 240 BFS 360 BFS 480
High-shear granulator GMA 70 BFS 150 GMA 300 GMA 600 GMA 800 GMA 1200
Working volume product container [L] 9 - 90 30 - 120 60 - 240 120 - 480 180 - 720 240 - 960
Number of product filter bags 6 7 9 12 12 14
Number of nozzles (tangential spray) 2 3 4 5 6 8

The following list gives you an initial overview and comparison of our various Compact Granulation Systems for your Wet Granulation and Drying.

Variants of the Compact Granulation System

We offer our Compact Granulation Systems in different sizes and technical designs.You can download our Product Brochures for Wet Granulation and Drying with the Compact Granulation System here:

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Facts and answers

The system impresses with its small footprint, flexible application options and smooth production process. It integrates all the central process steps of Wet Granulation and drying in one compact unit, making it ideal for GMP-compliant and efficient production.

The system combines the high-shear granulator (GMA), the wet screen (BTS), the fluidised bed processor (BFS) with Bohle Uni Cone BUC®, a cyclone separator and a dry screen.

A direct product transfer takes place via a closed stainless steel line from the GMA to the BFS. Additional integrated emptying and transfer valves enable a continuous process flow without conversions, which saves time and minimises the risk of Cross-contamination.

The Bohle Uni Cone BUC® technology ensures complete fluidisation of the particles and uniform filming. The result: maximum product quality, short cleaning times thanks to the WIP system and an ergonomic, economical solution for optimising classic wet granulation processes.

Make an enquiry now

Do you have any questions about our machines, services or solutions? Our team will be happy to help you! Get in touch with us. We will advise you individually and work with you to find the best solution for your requirements. We look forward to your enquiry!

Joschka Raby

Area Sales Manager

Your application in our test centre

See for yourself and test our machines directly on site in our Service Centre and Technology Centre. Our competent and experienced team is at your disposal for test series or process optimisation in order totake your processes to a higher level. We offer you the opportunity to carry out practical tests to evaluate the efficiency, quality and Scalability of your processes. You benefit from state-of-the-art technology, comprehensive advice and customised support. Visit us and discover how our machines and processes can optimise your production processes and product quality.

Therefore L.B. Bohle

Innovative technologies

As a technology leader for tablet production machines, we offer innovative solutions for every process step from development to large batches.

Customised solutions

L.B. Bohle develops and realises customised, highly complex machine solutions that are perfectly tailored to your requirements and production goals.

Support and customer service

L.B. Bohle is always at your side. With short response times and a clear focus on solutions, we are always reliably at your disposal - personally, competently and practically.

Sustainability

Sustainability is firmly anchored in all areas of the company. We make targeted investments in infrastructure and research to make our machines even more efficient and environmentally friendly.

High-tech pharmaceutical machinery "Made in Germany". With our extensive product portfolio, we optimise your pharmaceutical solids production. Find out more about the company now.

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