For the pharmaceutical industry, L.B. Bohle offers flexible, economical and resource-saving technology solutions for coating tablets that optimise the production process. The product range includes laboratory and production-scale systems that enable a wide range of options and product extensions to ensure an efficient and sustainable mixing process.
L.B. Bohle offers you a comprehensive range of state-of-the-art machines and systems for your tablet production. Individually tailored to your requirements, our machines optimise your production processes and ensure optimum quality. Our machine finder will guide you quickly and easily to the optimum solution for your processes.
With L.B. Bohle, you can achieve the highest production efficiency and maximum product quality.
Tablet Coating or film coating is a crucial and demanding process step in tablet production in the pharmaceutical industry. L.B. Bohle is the technology leader on the market with its range of coating systems for pharmaceutical applications.
Tablet Coating or film coating processes are divided into the basic operations
- Spraying
- Mixing
- Drying
Each individual operation must be carefully optimised in coordination with the others.
The coaters from L.B. Bohle guarantee first-class product processing with high profitability. Optimum running of the cores is ensured by a flat tablet bed in a long drum geometry and infinitely variable adjustment of the angle of inclination. The systematic forced guidance in the drum ensures constant movement of the product. No twins are formed. Solids and paint loss are minimal.
Tablet Coating
Tablet Coating involves applying a thin layer of polymers and other excipients such as colourants or humectants to the tablet. This coating fulfils several functions: It can specifically control the release of the active ingredient, protect the active ingredient from light, moisture or oxygen, mask unpleasant flavours and improve the swallowability of the tablet.
Active Pharmaceutical Ingredient (API) coating
Active Pharmaceutical Ingredient (API) coating is becoming increasingly important. Tablets are specifically coated with one or more Active Pharmaceutical Ingredients (API), for example in combination preparations or for incompatible APIs. Tablet Coating also enables the combination of different release profiles within one tablet: while the core contains the slow-release component, the film coating provides the immediate initial dose.
Uniformity
Complex coating formulations can contain up to four different film coatings, which leads to longer process times. In order to achieve efficient and regulatory-compliant results, high coating uniformity, i.e. the uniformity of the tablet coating, is of central importance.
Product protection
In addition to controlling the release, the Tablet Coating offers further functional benefits. It reliably protects the tablet from external influences such as light, air or moisture and thus contributes to stability and extended shelf life.
Sensors
The sensory properties of the tablets can also be specifically improved by coating. Flavour or olfactory self-protection (e.g. for bitter or strong-smelling Active Pharmaceutical Ingredients (API)) and better swallowability increase patient acceptance.
Coloured masking
Another advantage of Tablet Coating is the possibility of colour coding. Coloured coatings make it easier to visually distinguish between different products and can also be used as a brand-defining element.
Coating systems
Specialised Tablet Coating systems / Tablet Coaters are used to reliably implement all of these functions. They ensure a uniform, validatable and reproducible coating and high uniformity. This is a decisive factor for quality, efficacy and regulatory safety.
Tablet Coaters or Tablet Coating systems are used in the chemical, food and pharmaceutical industries. They are also used in the manufacture of food supplements. Astablets are the most common form of oral drug administration, Tablet Coating is a key factor in their quality, efficacy and safety. Tablet Coaters are used from Research & Development through to high-volume production. In addition to efficiency , coating uniformity is also crucial. Coating uniformity (uniformity of the tablet coating) is indicated by the relative standard deviation (RSD) and has a high analytical significance. The lower the RSD value, the more uniform the tablet coating.
L.B. Bohle offers a comprehensive range of Tablet Coaters for coating tablets. The BFC Film Coater is the high-end system. Outstanding coating results are also achieved with the BTC Tablet Coater. The BFC 50 Tripan Tablet Coater stands for maximum flexibility thanks to its three interchangeable drums. The BFC 5 Laboratory Coater is the first choice on the market for Research & Development or small batches. L.B. Bohle also sets the standard in Continuous Manufacturing with the semi-continuous Coater - KOCO®.
