Grinding and Conical Sieves are indispensable for precise and valid production processes in the pharmaceutical, chemical and food industries. Grinding and Conical Sieves play a decisive role in tablet production for the pharmaceutical industry: they ensure a homogeneous particle size distribution - the basis for reproducible processes and high-quality tablets.
Grinding and Conical Sieves are used to crush solids . This comminution has two objectives:
- To increase the particle surface area in order to increase the dissolution rate
- To equalise different Particle Sizes to ensure homogeneous miscibility.
It is precisely because of their versatility that mills and Conical Sieves play a decisive role in pharmaceutical production. They can be integrated into complex production lines, e.g. for filling/emptying or transfer processes on process machines or for filling and transferring containers.
Grinding and Conical Sieves have one goal: toensure optimum quality in the process. Grinding and Conical Sieves are used to reduce agglomerates, homogenise the Particle Size or classify fine powders.
Grinding and Conical Sieves must be highly flexible , easy to operate and clean and, above all, guarantee a high level of Process Safety.
GMP standards
Grinding and Conical Sieves must comply with Good Manufacturing Practice (GMP) standards to ensure reproducible processes and documented quality assurance.
Hygienic design and cleaning
It is crucial that the materials, surfaces and structural elements can be cleaned easily, quickly and completely . All surfaces and connections of the Grinding and Conical Sieve machines must be smooth and without indentations. These must also be avoided or minimised when designing connections. In addition, weld seams and seals must not be a quality criterion.
Cleaning-in-place (CIP) is used for the automated cleaning of production systems in the pharmaceutical industry. Residues and microorganisms are removed from surfaces in the process or grinding chambers.
Washing in Place (WIP) is an automated cleaning process in which the cleaning system is used directly in the production environment. Grinding and Conical Sieves are cleaned in a closed-loop system, which reduces the risk of Cross-contamination and improves efficiency.
Flexibility and Scalability
Grinding and Conical Sieves can be integrated into complex production lines. Thanks to their mobility, they can bequickly movedto other rooms for use or cleaning . Grinding and Conical Sieves are generally characterised by high Throughputs.
Safety and ergonomics
User and operator protection must be guaranteed at all times with Grinding and Conical Sieves. The best possible protection for employees, the environment and the process is also ensured for containment applications. The use of proven components guarantees a high level of Process Safety and stability of the process. This is the ideal basis for the construction of containment components.
Grinding and Conical Sieves must be user-friendly and easy to maintain. This means that all parts must be easy to operate and reach. Disassembly without tools or with few tools is preferable.
Certifications
Grinding and Conical Sieves must comply with GMP requirements and fulfil the FDA and EU GMP guidelines. ATEX certification (explosion protection) for processes with a dust hazard is also possible.
Compliance with these standards is not only crucial for the safety and quality of the products, but also for the authorisation of pharmaceutical drugs in different countries.
The advantages of our Grinding and sieving systems
Homogeneous particle size distribution for reproducible processes: Uniform Particle Sizes ensure optimum miscibility and consistent tablet quality.
Flexibility and integration into existing processes: Whether as a mobile unit or a permanently integrated solution. Grinding and Conical Sieves are versatile.
Convenient cleaning and GMP-compliant hygienic design: Smooth surfaces, CIP/WIP cleaning and virtually tool-free disassembly enable fast, safe cleaning.
Process Safety and operator protection: Ergonomic design, high user-friendliness, containment options and certified safety standards (e.g. ATEX) ensure safe operation.
Scalability and efficiency : Wide production range: Grinding and Conical Sieves are ideal for research and development, pilot production and large-scale production.
{{ product.categoryLabel }}
Weltneuheit
{{ product.title }}
{{ product.link }}
{{ product.subtitle }}
{{ product.description }}
L.B. Bohle offers you a comprehensive range of state-of-the-art machines and systems for your tablet production. Individually tailored to your requirements, our machines optimise your production processes and ensure optimum quality. Our machine finder will guide you quickly and easily to the optimum solution for your processes.
With L.B. Bohle, you can achieve the highest production efficiency and maximum product quality.
