Metformin preparation station - tablet production with metformin

With the new Metformin preparation station, L.B. Bohle enables efficient and large-volume processing of Metformin.

Tablet production with metformin: Combination of lump breaker and conical sieve mill BTS
Metformin (chemically 1,1-dimethylbiguanide) is used to lower blood sugar levels in the treatment of non-insulin-dependent type 2 diabetes and obesity, making it one of the most important drugs. Metformin lowers the blood sugar level by interfering with the glucose metabolism in several ways, thus reducing the release of sugar from the liver and improving the insulin sensitivity of the body's cells. Metformin is inexpensive to produce and is required in large quantities. It has long been recognised as a standard medication for type 2 diabetes and demand is high worldwide. In Germany alone, there are Sieving million people suffering from diabetes, 90% of whom have type 2 diabetes.

Metformin preparation station for efficient production
With the new metformin preparation station, L.B. Bohle enables efficient and large-volume processing of metformin. The mobile station crushes, de-clumps and Sieves the Metformin before transferring it by vacuum to the BFS fluidised bed system positioned next to it. The raw material is in the form of solid blocks, is manually unpacked by the operator and placed on a lifting device at an ergonomic height. The platform with the product is lifted using convenient controls on the HMI and the Metformin block is fed to the chopper unit. Complete dust extraction is guaranteed at all times via an extraction system.

Flexible use thanks to various sieve inserts
A Bohle Turbo Sieve (BTS) is connected directly under the chopper unit, which sieves the shredded Metformin blocks. Various screen inserts with different diameters can be used. A suction shoe is connected to the outlet of the BTS, which establishes a connection to the vacuum transfer system of the Bohle fluidised bed system.

Advantages at a glance

  • Compact design - mobile use thanks to trolley
  • Convenient operation of the machine via HMI. Only one operator is required to load the machine.
  • Fast unpacking of the Metformin blocks at an ergonomic height
  • Short production cycle - approx. 40 seconds
  • Quick disassembly for Cleaning. A Lifting Columns is required for the complete disassembly of the feed hopper and chopper.
  • High flexibility through the use of different sieve inserts
  • Integrated vibrator or beater
  • Inspection of the process - clear view of the feed hopper and chopper

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Markus Beckmann

Manager Finance and HR